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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC23B
All Species:
39.39
Human Site:
Y680
Identified Species:
72.22
UniProt:
Q15437
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15437
NP_006354.2
767
86479
Y680
G
Y
Q
D
M
P
E
Y
E
N
F
K
H
L
L
Chimpanzee
Pan troglodytes
XP_001140754
767
86435
Y680
G
Y
Q
D
M
P
E
Y
E
N
F
K
H
L
L
Rhesus Macaque
Macaca mulatta
XP_001091771
765
86128
Y678
G
Y
Q
D
M
P
E
Y
E
N
F
R
H
L
L
Dog
Lupus familis
XP_534332
767
86392
Y680
G
Y
Q
D
M
P
E
Y
E
N
F
K
H
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D662
767
86419
Y680
G
Y
Q
D
M
P
E
Y
E
N
F
K
H
L
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513018
765
86087
Y678
G
Y
Q
D
M
P
E
Y
E
N
F
R
H
L
L
Chicken
Gallus gallus
Q5ZK03
767
86285
Y680
G
Y
Q
D
M
P
E
Y
E
N
F
K
H
L
L
Frog
Xenopus laevis
NP_001086405
741
83183
L660
E
Y
E
N
F
K
Q
L
L
Q
A
P
L
D
D
Zebra Danio
Brachydanio rerio
Q7SZE5
765
86062
Y678
G
Y
Q
D
M
P
E
Y
E
N
F
R
H
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392515
768
85881
Y681
K
Y
Q
D
L
P
E
Y
E
N
F
R
Q
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780042
764
86244
E679
F
H
E
Q
D
G
H
E
N
F
K
Q
L
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15303
768
85366
Y684
G
Y
Q
D
D
P
Q
Y
A
D
F
K
A
L
L
Red Bread Mold
Neurospora crassa
Q9C284
775
86260
G683
A
G
Y
Q
D
Q
E
G
Y
E
N
F
A
A
L
Conservation
Percent
Protein Identity:
100
99.4
84.7
97.6
N.A.
97.1
N.A.
N.A.
84.7
93
88.6
85.5
N.A.
N.A.
73.5
N.A.
75.8
Protein Similarity:
100
99.6
92.5
98.9
N.A.
98.5
N.A.
N.A.
92.4
96.6
92.1
91.6
N.A.
N.A.
85.4
N.A.
85.6
P-Site Identity:
100
100
93.3
100
N.A.
100
N.A.
N.A.
93.3
100
6.6
93.3
N.A.
N.A.
73.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
26.6
100
N.A.
N.A.
86.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
51
57.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
68.2
71.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
8
0
8
0
16
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
77
24
0
0
0
0
8
0
0
0
8
8
% D
% Glu:
8
0
16
0
0
0
77
8
70
8
0
0
0
0
0
% E
% Phe:
8
0
0
0
8
0
0
0
0
8
77
8
0
0
0
% F
% Gly:
70
8
0
0
0
8
0
8
0
0
0
0
0
0
8
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
62
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
8
0
0
0
0
8
47
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
8
8
0
0
0
16
85
85
% L
% Met:
0
0
0
0
62
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
8
70
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
77
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
77
16
0
8
16
0
0
8
0
8
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
31
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
85
8
0
0
0
0
77
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _